Expression of aryl hydrocarbon receptor 1 (AHR1), AHR1 nuclear translocator 1 (ARNT1) and CYP1 family monooxygenase mRNAs and their activity in chicken ovarian follicles following in vitro exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Issue 2 (2nd September 2015)

• Record Type: Journal Article
• Authors: Antos, Piotr A.; Błachuta, Małgorzata; Hrabia, Anna; Grzegorzewska, Agnieszka K.; Sechman, Andrzej
• Is Part Of: Toxicology letters. Volume 237:Issue 2(2015)
• Page Start: 100
• Page End: 111
• Publication Date: 2015-09-02
• Subjects: Toxicology -- Periodicals; 363.179
• DOI: 10.1016/j.toxlet.2015.05.020
• Languages: English
• ISSNs: 0378-4274

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0050"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Chicken ovarian follicles express <italic>AHR1</italic>, <italic>ARNT1</italic> and <italic>CYP1</italic>-family monooxygenases.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">TCDD and LH affect <italic>AHR1</italic>, <italic>ARNT1</italic>, <italic>CYP1A4</italic>, <italic>A5</italic> and <italic>B1</italic> expression in chicken ovary.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">TCDD induces EROD and MROD activities both in white and yellow follicles.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">The avian ovary is an organ of dioxin and dioxin-like compounds detoxification.</p> </list-item> </list> </p> </sec> </abstract>