ErbB small molecule tyrosine kinase inhibitor (TKI) induced diarrhoea: Chloride secretion as a mechanistic hypothesis. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Van Sebille, Ysabella Z.A.; Gibson, Rachel J.; Wardill, Hannah R.; Bowen, Joanne M.
• Is Part Of: Cancer treatment reviews. Volume 41:Issue 7(2015)
• Page Start: 646
• Page End: 652
• Publication Date: 2015-07
• Subjects: Cancer -- Periodicals; Cancer -- Treatment -- Periodicals; Neoplasms -- therapy -- Periodicals; Cancer -- Périodiques; Cancer -- Traitement -- Périodiques; Cancer -- Treatment; Electronic journals; Periodicals; 616.99406
• DOI: 10.1016/j.ctrv.2015.05.011
• Languages: English
• ISSNs: 0305-7372

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title id="st005">Highlights</title> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">The mechanisms of ErbB TKI-induced diarrhoea are likely different to chemotherapy.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">This paper provides rationale for chloride secretion as a mechanistic hypothesis.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">This paper reviews current management of ErbB TKI-induced diarrhoea.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">This paper speculates on potential new therapies for ErbB TKI-induced diarrhoea.</p> </list-item> </list> </p> </sec> </abstract>