Binding of Anticell Adhesive Oxime‐Crosslinked PEG Hydrogels to Cardiac Tissues. Issue 9 (12th May 2015)

• Record Type: Journal Article
• Authors: Grover, Gregory N.; Garcia, Julian; Nguyen, Mary M.; Zanotelli, Matthew; Madani, Michael M.; Christman, Karen L.
• Is Part Of: Advanced healthcare materials. Volume 4:Issue 9(2015)
• Page Start: 1327
• Page End: 1331
• Publication Date: 2015-05-12
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201500167
• Languages: English
• ISSNs: 2192-2640

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adhm201500167-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Postsurgical cardiac adhesions</bold> increase the number of surgeries as well as patient mortality and morbidity. A fast gelling oxime‐crosslinked PEG hydrogel with tunable gelation time, degradation, and mechanical properties is presented. This material is cytocompatible and prevents cellular adhesion. Material retention on different cardiac tissues is demonstrated ex vivo over time and that functional group ratio alters material retention on different cardiac tissues. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgj14nkkr2n" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>