Stereogenic α-carbons determine the shape and topology of [13]-macrodilactones1. Issue 18 (14th May 2015)

• Record Type: Journal Article
• Authors: Magpusao, Anniefer N.; Rutledge, Kelli; Mercado, Brandon Q.; Peczuh, Mark W.
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 18(2015)
• Page Start: 5086
• Page End: 5089
• Publication Date: 2015-05-14
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00402k
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj14j7htzb" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The configuration of α-stereogenic centers affects the shape and topology of [13]-macrodilactones. When one α-stereogenic center is substituted, it directs the planar chirality of the macrocycle; when two centers are substituted, both the shape and the topology are influenced.</p> </abstract>