Cyclodextrin–peptide conjugates for sequence specific DNA binding1. Issue 18 (14th May 2015)

• Record Type: Journal Article
• Authors: Ruiz García, Yara; Zelenka, Jan; Pabon, Y. Vladimir; Iyer, Abhishek; Buděšínský, Miloš; Kraus, Tomáš; Edvard Smith, C. I.; Madder, Annemieke
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 18(2015)
• Page Start: 5273
• Page End: 5278
• Publication Date: 2015-05-14
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00609k
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj14j7j0bg" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />CD–peptide conjugates were synthesized <italic>via</italic> CuAAC. Though the CD cavity size was shown to influence the binding affinity of the compounds, all constructs recognize and bind the cognate CRE dsDNA.</p> </abstract>