A metabolomic study of adipose tissue in mice with a disruption of the circadian system1. Issue 7 (16th July 2015)

• Record Type: Journal Article
• Authors: Castro, C.; Briggs, W.; Paschos, G. K.; FitzGerald, G. A.; Griffin, J. L.
• Is Part Of: Molecular bioSystems. Volume 11:Issue 7(2015:Jul.)
• Page Start: 1897
• Page End: 1906
• Publication Date: 2015-07-16
• Subjects: Molecular biology -- Periodicals; Biochemistry -- Periodicals; 571.7405
• DOI: 10.1039/c5mb00032g
• Languages: English
• ISSNs: 1742-206X

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj146rpg2t" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Metabolomics has been used to analyse adipose tissue in mice with an adipocyte-specific deletion of <italic>Arntl</italic>, showing the importance of the peripheral circadian clock in metabolic regulation. <italic>Arntl</italic> induces global changes in both white and brown adipose tissues which were distinct for the two tissues.</p> </abstract>