<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>2‐Chloro‐4‐(2, 3, 5, 6‐tetrafluorophenoxy)pyrimidine (I) can be diaminated in a regioselective stepwise manner: first amination occurs at C‐2, second amination at C‐4.</p> </abstract>