Conditional net survival: Relevant prognostic information for colorectal cancer survivors. A French population-based study. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Drouillard, Antoine; Bouvier, Anne-Marie; Rollot, Fabien; Faivre, Jean; Jooste, Valérie; Lepage, Côme
• Is Part Of: Digestive and liver disease. Volume 47:Issue 7(2015)
• Page Start: 597
• Page End: 601
• Publication Date: 2015-07
• Subjects: Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; 616.33005
• DOI: 10.1016/j.dld.2015.03.013
• Languages: English
• ISSNs: 1590-8658

Abstract

<abstract abstract-type="author" id="abs0005"> <title id="sect0005">Abstract</title> <sec> <title id="sect0010">Background</title> <p id="spar0005">Traditionally, survival estimates have been reported as survival from the time of diagnosis. A patient's probability of survival changes according to time elapsed since the diagnosis and this is known as conditional survival. The aim was to estimate 5-year net conditional survival in patients with colorectal cancer in a well-defined French population at yearly intervals up to 5 years.</p> </sec> <sec> <title id="sect0015">Methods</title> <p id="spar0010">Our study included 18, 300 colorectal cancers diagnosed between 1976 and 2008 and registered in the population-based digestive cancer registry of Burgundy (France). We calculated conditional 5-year net survival, using the Pohar Perme estimator, for every additional year survived after diagnosis from 1 to 5 years.</p> </sec> <sec> <title id="sect0020">Results</title> <p id="spar0015">The initial 5-year net survival estimates varied between 89% for stage I and 9% for advanced stage cancer. The corresponding 5-year net survival for patients alive after 5 years was 95% and 75%. Stage II and III patients who survived 5 years had a similar probability of surviving 5 more years, respectively 87% and 84%. For survivors after the first year following diagnosis, five-year conditional net survival was similar regardless of age class and period of diagnosis.</p> </sec> <sec> <title id="sect0025">Conclusions</title> <p id="spar0020">For colorectal cancer survivors, conditional net survival provides relevant and complementary prognostic information for patients and clinicians.</p> </sec> </abstract>