Vertical Nanowire Electrode Arrays as Novel Electrochemical Label‐Free Immunosensors. Issue 24 (11th February 2015)

• Record Type: Journal Article
• Authors: Nasr, Babak; Chana, Gursharan; Lee, Ting Ting; Nguyen, Thanh; Abeyrathne, Chathurika; D'Abaco, Giovanna M.; Dottori, Mirella; Skafidas, Efstratios
• Is Part Of: Small. Volume 11:Issue 24(2015)
• Page Start: 2862
• Page End: 2868
• Publication Date: 2015-02-11
• Subjects: Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201403540
• Languages: English
• ISSNs: 1613-6810

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="smll201403540-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>A new method for the fabrication of a label‐free electrochemical immunosensor</bold> based on vertical nanowires (VNWs) is proposed. The VNWs are functionalized to detect antibodies against a major astrocytic structural protein component, glial fibrillary acidic protein (GFAP). It is revealed that the interaction of GFAP‐antibody with functionalized VNWs leads to a clear change in device conductance and the corresponding capacitance. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgj111ftpd4" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>