Iridium‐Catalyzed Enantioselective Allylic Alkylation with Functionalized Organozinc Bromides1. (12th May 2015)
- Record Type:
- Journal Article
- Title:
- Iridium‐Catalyzed Enantioselective Allylic Alkylation with Functionalized Organozinc Bromides1. (12th May 2015)
- Main Title:
- Iridium‐Catalyzed Enantioselective Allylic Alkylation with Functionalized Organozinc Bromides1
- Authors:
- Hamilton, James Y.
Sarlah, David
Carreira, Erick M. - Abstract:
- <abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Iridium‐catalyzed enantioselective allylic alkylation of branched racemic carbonates with functionalized alkylzinc bromide reagents is described. Enabled by a chiral Ir/(P, olefin) complex, the method described allows allylic substitution with various primary and secondary alkyl nucleophiles with excellent regio‐ and enantioselectivities. The developed reaction was showcased in a concise, asymmetric synthesis of (−)‐preclamol.</p> </abstract>
- Is Part Of:
- Angewandte Chemie. Volume 127:Number 26(2015)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 127:Number 26(2015)
- Issue Display:
- Volume 127, Issue 26 (2015)
- Year:
- 2015
- Volume:
- 127
- Issue:
- 26
- Issue Sort Value:
- 2015-0127-0026-0000
- Page Start:
- 7754
- Page End:
- 7757
- Publication Date:
- 2015-05-12
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201501851 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 4077.xml