Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA1. Issue 26 (12th May 2015)

• Record Type: Journal Article
• Authors: Buceta, David; Busto, Natalia; Barone, Giampaolo; Leal, José M.; Domínguez, Fernando; Giovanetti, Lisandro J.; Requejo, Félix G.; García, Begoña; López‐Quintela, M. Arturo
• Is Part Of: Angewandte Chemie international edition. Volume 54:Issue 26(2015)
• Page Start: 7612
• Page End: 7616
• Publication Date: 2015-05-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201502917
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Subnanometric samples, containing exclusively Ag₂ and Ag₃ clusters, were synthesized for the first time by kinetic control using an electrochemical technique without the use of surfactants or capping agents. By combination of thermodynamic and kinetic measurements and theoretical calculations, we show herein that Ag₃ clusters interact with DNA through intercalation, inducing significant structural distortion to the DNA. The lifetime of Ag₃ clusters in the intercalated position is two to three orders of magnitude longer than for classical organic intercalators, such as ethidium bromide or proflavine.</p> </abstract>