Single versus double flap approach in periodontal regenerative treatment. (29th May 2015)

• Record Type: Journal Article
• Authors: Schincaglia, Gian Pietro; Hebert, Eric; Farina, Roberto; Simonelli, Anna; Trombelli, Leonardo
• Is Part Of: Journal of clinical periodontology. Volume 42:Number 6(2015:Jun.)
• Page Start: 557
• Page End: 566
• Publication Date: 2015-05-29
• Subjects: Periodontics -- Periodicals; 617.6
• DOI: 10.1111/jcpe.12409
• Languages: English
• ISSNs: 0303-6979

Abstract

<abstract abstract-type="main" id="jcpe12409-abs-0001"> <title>Abstract</title> <sec id="jcpe12409-sec-0001" sec-type="section"> <title>Aim</title> <p>to compare the outcomes of a regenerative strategy based on recombinant human platelet‐derived growth factor–BB (rhPDGF‐BB, 0.3 mg/ml) and <italic>β</italic>‐tricalcium phosphate (<italic>β</italic>‐TCP) in the treatment of intraosseous defects accessed with the Single Flap Approach (SFA) <italic>versus</italic> Double Flap Approach based on papilla preservation techniques (DFA).</p> </sec> <sec id="jcpe12409-sec-0002" sec-type="section"> <title>Materials and Methods</title> <p>Fifteen and 13 defects, randomly assigned to SFA or DFA, respectively, were grafted with rhPDGF‐BB + <italic>β</italic>‐TCP. Probing parameters were assessed before and 6 months after surgery. Pain (VAS<sub>pain</sub>) was self‐reported using a visual analogue scale.</p> </sec> <sec id="jcpe12409-sec-0003" sec-type="section"> <title>Results</title> <p>Twelve SFA sites and DFA 6 sites showed complete flap closure at 2 weeks post‐surgery. No significant differences in 6‐month changes in probing parameters and radiographic defect fill were found between groups. Significantly lower VAS<sub>pain</sub> was observed in SFA group compared to DFA group at day +1, +2 and +6. A significantly greater number of analgesics were consumed in the DFA group compared to the SFA group at day +1.</p> </sec> <sec id="jcpe12409-sec-0004" sec-type="section"> <title>Conclusions</title> <p>When combined with rhPDGF‐BB and <italic>β</italic>‐TCP, the SFA may result in similar clinical outcomes, better quality of early wound healing, and lower pain and consumption of analgesics during the first postoperative days compared to the DFA.</p> </sec> </abstract>