Osteopontin, CCL5 and CXCL9 are independently associated with psoriasis, regardless of the presence of obesity. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Duarte, G.V.; Boeira, V.; Correia, T.; Porto-Silva, L.; Cardoso, T.; Macedo, M.N.; Oliveira, M.F.; Carvalho, E.
• Is Part Of: Cytokine. Volume 74:Issue 2(2015)
• Page Start: 287
• Page End: 292
• Publication Date: 2015-08
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.04.015
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">OPN, CCL5 and CXCL9 levels are higher in psoriasis patients than controls, regardless of obesity.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">OPN plasma levels are highly (OR = 19.25) associated with occurrence of psoriasis.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">CCL2 levels are higher in obese than non-obese psoriasis patients.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">Facial involvement and PASI are not associated to OPN, CCL5, CCL2 or CXCL9 elevation.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0025">No correlation was found between OPN and CXCL9 as well as between OPN and TNF.</p> </list-item> </list> </p> </sec> </abstract>