The βc receptor family – Structural insights and their functional implications. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Broughton, Sophie E.; Nero, Tracy L.; Dhagat, Urmi; Kan, Winnie L.; Hercus, Timothy R.; Tvorogov, Denis; Lopez, Angel F.; Parker, Michael W.
• Is Part Of: Cytokine. Volume 74:Issue 2(2015)
• Page Start: 247
• Page End: 258
• Publication Date: 2015-08
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.02.005
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st110">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0190">GM-CSF and IL-3 are pleiotropic cytokines with roles in health and disease.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0195">New crystal structure of IL3Rα reveals novel open and closed conformations.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0200">Membrane proximal and transmembrane domain movement likely to initiate signaling.</p> </list-item> </list> </p> </sec> </abstract>