Smac mimetic and oleanolic acid synergize to induce cell death in human hepatocellular carcinoma cells. Issue 1 (28th August 2015)

• Record Type: Journal Article
• Authors: Liese, Juliane; Abhari, Behnaz Ahangarian; Fulda, Simone
• Is Part Of: Cancer letters. Volume 365:Issue 1(2015)
• Page Start: 47
• Page End: 56
• Publication Date: 2015-08-28
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2015.04.018
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">Synthetic lethal interaction of Smac mimetic and oleanolic acid in hepatocellular carcinoma.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Cell death caused by combination treatment is ROS-dependent.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">Smac mimetic and oleanolic acid cooperate to suppress tumor growth <italic>in vivo</italic>.</p> </list-item> </list> </p> </sec> </abstract>