Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism. Issue 1 (28th August 2015)

• Record Type: Journal Article
• Authors: Cheng, Gang; Zielonka, Jacek; McAllister, Donna; Hardy, Micael; Ouari, Olivier; Joseph, Joy; Dwinell, Michael B.; Kalyanaraman, Balaraman
• Is Part Of: Cancer letters. Volume 365:Issue 1(2015)
• Page Start: 96
• Page End: 106
• Publication Date: 2015-08-28
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2015.05.016
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">Mitochondria-targeted antioxidants (MTAs) inhibit proliferation of cancer cells.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Radical scavenging properties are not necessary for antiproliferative effects of MTAs.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">Inhibition of bioenergetic function is a common feature of different MTAs.</p> </list-item> </list> </p> </sec> </abstract>