Stereoselective synthesis of 2-acetamido-1, 2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors1. Issue 23 (21st June 2015)

• Record Type: Journal Article
• Authors: de la Fuente, Alex; Mena-Barragán, Teresa; Farrar-Tobar, Ronald A.; Verdaguer, Xavier; García Fernández, José M.; Ortiz Mellet, Carmen; Riera, Antoni
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 23(2015)
• Page Start: 6500
• Page End: 6510
• Publication Date: 2015-06-21
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00507h
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj1018g463" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A novel approach to the synthesis of 2-acetamido-1, 2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as potent hexosaminidase inhibitors is reported.</p> </abstract>