Simple and fast electrochemical detection of sequence-specific DNA via click chemistry-mediated labeling of hairpin DNA probes with ethynylferrocene. Issue 12 (21st June 2015)

• Record Type: Journal Article
• Authors: Hu, Qiong; Deng, Xianbao; Kong, Jinming; Dong, Yuanyuan; Liu, Qianrui; Zhang, Xueji
• Is Part Of: Analyst. Volume 140:Issue 12(2015)
• Page Start: 4154
• Page End: 4161
• Publication Date: 2015-06-21
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c5an00566c
• Languages: English
• ISSNs: 0003-2654

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj1017p183" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />In this work, the azido-containing hairpins were exploited as the capture probes; after hybridization, labeling of electroactive probes, ethynylferrocene, was conveniently and efficiently achieved <italic>via</italic> the Cu(<sc>i</sc>)-catalyzed azide–alkyne cycloaddition.</p> </abstract>