Functional characterisation of a TLR accessory protein, UNC93B1, in Atlantic salmon (Salmo salar). Issue 1 (May 2015)

• Record Type: Journal Article
• Authors: Lee, P.T.; Zou, J.; Holland, J.W.; Martin, S.A.M.; Scott, C.J.W.; Kanellos, T.; Secombes, C.J.
• Is Part Of: Developmental and comparative immunology. Volume 50:Issue 1(2015)
• Page Start: 38
• Page End: 48
• Publication Date: 2015-05
• Subjects: Immunology -- Periodicals; Developmental immunology -- Periodicals; 616.079
• DOI: 10.1016/j.dci.2014.12.014
• Languages: English
• ISSNs: 0145-305X

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">We have identified the UNC93B1 gene in Atlantic salmon.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">The phylogenetic status was verified.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">The expression profiles in different tissues and lifecycle stages have been studied.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">The expression of salmon UNC93B1 was modulated by polyI:C and IFNγ.</p> </list-item> <list-item id="u0030"> <label></label> <p id="p0030">The physical interaction of wild type and site mutated (H424R) UNC93B1 and salmon TLR19, TLR20a and TLR20d was examined.</p> </list-item> </list> </p> </sec> </abstract>