Alterations of a spectrum of driver genes in female Chinese patients with advanced or metastatic squamous cell carcinoma of the lung. Issue 2 (February 2015) - Qiong, Zhao
Highlights We analyzed molecular abnormalities in Chinese females with advanced SQCLC. Three specificities of female SQCLCs were observed: less smoking history, younger age and more peripheral type. No significant differences in EGFR, KRAS, EML4-ALK, PTEN and FGFR1 between different genders were found. Significant lower frequency of PIK3CA mutation was detected in females.