Super‐resolution reconstruction of late gadolinium‐enhanced MRI for improved myocardial scar assessment. Issue 1 (19th September 2014)

• Record Type: Journal Article
• Authors: Dzyubachyk, Oleh; Tao, Qian; Poot, Dirk H.J.; Lamb, Hildo J.; Zeppenfeld, Katja; Lelieveldt, Boudewijn P.F.; van der Geest, Rob J.
• Is Part Of: Journal of magnetic resonance imaging. Volume 42:Issue 1(2015)
• Page Start: 160
• Page End: 167
• Publication Date: 2014-09-19
• Subjects: Magnetic resonance imaging -- Periodicals; 616
• DOI: 10.1002/jmri.24759
• Languages: English
• ISSNs: 1053-1807

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jmri24759-sec-0001" sec-type="section"> <title>Purpose</title> <p>To develop and validate a method for improving image resolution of late gadolinium‐enhanced (LGE) magnetic resonance imaging (MRI) for accurate assessment of myocardial scar.</p> </sec> <sec id="jmri24759-sec-0002" sec-type="section"> <title>Materials and Methods</title> <p>In a cohort of 37 postinfarction patients, LGE was performed prior to ventricular tachycardia catheter ablation therapy at 1.5T. A super‐resolution reconstruction (SRR) technique was applied to the three anisotropic views: short‐axis (SA), two‐chamber, and four‐chamber, to reconstruct a single isotropic volume. For compensation of the interscan heart motion, a joint localized gradient‐correlation‐based scheme was developed. Scar was identified as either core or gray zone in both the SRR and original SA volumes, and evaluated based on the clinically established bipolar voltage range of the in vivo electroanatomical voltage mapping (EAVM).</p> </sec> <sec id="jmri24759-sec-0003" sec-type="section"> <title>Results</title> <p>Compared to the SA volume, the SRR method resulted in significantly (<italic>P</italic> < 0.05) reduced myocardial scar gray zone sizes (10.5 ± 8.8 g vs. 9.2 ± 8.1 g) and improved agreement of the bipolar voltage range of scar gray zone (0.99 ± 0.65 mV vs. 1.46 ± 1.15 mV).</p> </sec> <sec id="jmri24759-sec-0004" sec-type="section"> <title>Conclusion</title> <p>We propose an SRR method to automatically reconstruct a high‐quality isotropic LGE volume from three orthogonal views. Analysis of the in vivo EAVM demonstrated improved myocardial scar assessment from the SRR volume compared with the SA LGE alone. <bold>J. Magn. Reson. Imaging 2015;42:160–167</bold>. © <bold>2014 Wiley Periodicals, Inc</bold>.</p> </sec> </abstract>