Asymmetric Borane Reduction of Prochiral Ketones Catalyzed By Helical Poly[(S)‐3‐vinyl‐2, 2'‐dihydroxy‐1, 1'‐binaphthyl]. Issue 7 (15th May 2015) - Qin, Guochang
Abstract The application of helical poly[(S)‐3‐vinyl‐2, 2'‐dihydroxy‐1, 1'‐binaphthyl] (L*) in the asymmetric borane reduction of prochiral ketones was studied. The results showed that L* had excellent catalytic activity as well as enantioselectivity, giving up to 96% yield and up to 99% enantiomeric excess (ee) of the corresponding secondary alcohol at 25 °C. Moreover, L* can be easily recovered and reused without loss of catalytic activity. Chirality 27:422–424, 2015. © 2015 Wiley Periodicals, Inc.