Malignant phyllodes tumor with osteosarcomatous differentiation metastasizing to small bowel and causing intestinal obstruction. Issue 4 (April 2015)

• Record Type: Journal Article
• Authors: Al-Rabiy, Fatma N.; Ali, Rola H.
• Is Part Of: Diagnostic histopathology. Volume 21:Issue 4(2015)
• Page Start: 165
• Page End: 168
• Publication Date: 2015-04
• Subjects: Histology, Pathological -- Periodicals; Cytodiagnosis -- Periodicals; Diagnosis, Laboratory -- Periodicals; Pathology -- Periodicals; Histopathologie -- Périodiques; Pathologie -- Périodiques; Cytodiagnostics -- Périodiques; Diagnostics biologiques -- Périodiques; Histologie -- Technique -- Périodiques; Electronic journals; 616.07582
• DOI: 10.1016/j.mpdhp.2014.09.001
• Languages: English
• ISSNs: 1756-2317

Abstract

<abstract xml:lang="en" abstract-type="author" id="abs0010"> <title id="sectitle0010">Abstract</title> <sec> <p id="abspara0010">Phyllodes tumors are relatively uncommon breast neoplasms constituting 0.3–1.0% of all breast tumors according to the 2012 World Health Organization book. Up to 10–20% of all phyllodes tumors are malignant and thus potentially capable of hematogenous metastatic spread particularly to the lungs and bones. Metastasis to the gastrointestinal tract, however, is unusual and might lead to diagnostic confusion particularly in the absence of relevant background clinical information. Phyllodes with osteosarcomatous and chondrosarcomatous heterologous differentiation may be particularly prone to metastasis. We report an unusual case of metastatic phyllodes tumor to small bowel that demonstrated extensive osteosarcomatous and chondrosarcomatous stromal elements.</p> </sec> </abstract>