Conservative management of neurocysticercosis in a patient with hematopoietic stem cell transplantation: a case report and review. Issue 3 (1st June 2015)

• Record Type: Journal Article
• Authors: Purvey, S.; Lu, K.; Mukkamalla, S.K.; Anandi, P.; Dumitriu, B.; Kranick, S.; Hammoud, D.A.; O'Connell, E.; Oh, A.L.; Barrett, J.; Mahanty, S.; Battiwalla, M.
• Is Part Of: Transplant infectious disease. Volume 17:Issue 3(2015)
• Page Start: 456
• Page End: 462
• Publication Date: 2015-06-01
• Subjects: Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12392
• Languages: English
• ISSNs: 1398-2273

Abstract

<abstract abstract-type="main" id="tid12392-abs-0001"> <title>Abstract</title> <p>Neurocysticercosis, an infection of the central nervous system with the larval stage of the cestode <italic>Taenia solium</italic>, is common in developing countries but its occurrence and management in allogeneic hematopoietic stem cell transplantation (HSCT) has not been reported previously, to our knowledge. We report the case of an immigrant female patient who underwent a matched‐related allogeneic HSCT for acute lymphoblastic leukemia and was incidentally found to have a solitary viable neurocysticercosis lesion. However, despite severe immunosuppression, the size of the cyst did not increase. More importantly, restoration of the immune system did not induce significant inflammation or seizures. Subsequent follow‐up demonstrated complete resolution of the neurocysticercosis lesion. Thus, in the setting of HSCT, an asymptomatic patient with a single neurocysticercosis lesion was successfully managed without the use of anthelmintics, steroids, or anti‐epileptics.</p> </abstract>