A novel recombinant BCG-expressing pro-apoptotic protein BAX enhances Th1 protective immune responses in mice. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Li, Guanghua; Liu, Guoyuan; Song, Na; Kong, Cong; Huang, Qi; Su, Haibo; Bi, Aixiao; Luo, Liulin; Zhu, Lin; Xu, Ying; Wang, Honghai
• Is Part Of: Molecular immunology. Volume 66:Issue 2(2015:Aug.)
• Page Start: 346
• Page End: 356
• Publication Date: 2015-08
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2015.04.003
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0040"> <list id="lis0010"> <list-item id="lsti0005"> <label></label> <p id="par0005">rBCG::BAX induces macrophage apoptosis <italic>in vitro</italic> and <italic>in vivo.</italic></p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">rBCG::BAX facilitates mycobacterial antigen presentation.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">rBCG::BAX enhances Th1 protective immune responses in mice.</p> </list-item> </list> </p> </sec> </abstract>