Evidence for TLR4 and FcRγ–CARD9 activation by cholera toxin B subunit and its direct bindings to TREM2 and LMIR5 receptors. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Phongsisay, Vongsavanh; Iizasa, Ei'ichi; Hara, Hiromitsu; Yoshida, Hiroki
• Is Part Of: Molecular immunology. Volume 66:Issue 2(2015:Aug.)
• Page Start: 463
• Page End: 471
• Publication Date: 2015-08
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2015.05.008
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0045"> <list id="lis0010"> <list-item id="lsti0005"> <label></label> <p id="par0005">Cholera toxin B subunit CTB possesses immunological properties.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">CTB activates TLR4 and FcRγ–CARD9 signaling pathway.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">CTB inhibits LMIR5 signaling triggered by 3-<italic>O</italic>-sulfo-β-<sc>d</sc>-galactosylceramide C24:1.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">CTB induces signal transduction through DAP12-coupled TREM2.</p> </list-item> </list> </p> </sec> </abstract>