IL-15-secreting γδT cells induce memory T cells in experimental allergic encephalomyelitis (EAE) mice. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Wang, Xiaoqian; Wei, Yinxiang; Liu, Xiaoling; Xing, Chen; Han, Gencheng; Chen, Guojiang; Hou, Chunmei; Dambuza, Ivy M.; Shen, Beifen; Li, Yan; Xiao, He; Wang, Renxi
• Is Part Of: Molecular immunology. Volume 66:Issue 2(2015:Aug.)
• Page Start: 402
• Page End: 408
• Publication Date: 2015-08
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2015.04.021
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">We identified a new subset of IL-15-secreting γδT (γδT15) cells.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">γδT15 cells were increased in EAE mice.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">γδT15 induced CD44^hi memory T cells by secreting IL-15.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">γδT15-induced memory T cells became into Th17 cells to induce EAE.</p> </list-item> </list> </p> </sec> </abstract>