Laser Suture Lysis After Trabeculectomy With Mitomycin C. Issue 5 (June 2015)

• Record Type: Journal Article
• Authors: Krömer, Maria; Nölle, Bernhard; Rüfer, Florian
• Is Part Of: Journal of glaucoma. Volume 24:Issue 5(2015:Jun./Jul.)
• Publication Date: 2015-06
• Subjects: Glaucoma -- Periodicals; 617.741005
• DOI: 10.1097/IJG.0000000000000144
• Languages: English
• ISSNs: 1057-0829

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Objective:</title> <p>This paper analyses to what extent positioning and timing influences the degree of intraocular pressure (IOP) reduction by laser suture lysis (LSL) after trabeculectomy with mitomycin C.</p> </sec> <sec> <title>Methods:</title> <p>The IOP reduction following LSL was assessed in a consecutive case series of 168 eyes (120 patients) after trabeculectomy with mitomycin C. Scleral flap sutures of 3.3±0.6 were placed on average. The IOP reduction was assessed in terms of suture positioning and the time of LSL.</p> </sec> <sec> <title>Results:</title> <p>LSL was performed early (<7 d) on 48 of 168 eyes (29%). The mean IOP before trabeculectomy was 22.1±5.9 and 20.3±6.2 mm Hg on the first postoperative day. LSL additionally reduced the IOP by 6.3±6.9 mm Hg. LSL was performed late (>7 d) on 27 of 168 eyes (16%). The mean preoperative IOP was 20.7±6.0 mm Hg, 12.1±7.8 mm Hg on the first postoperative day, and increased again to 21.7±4.5 mm Hg by the time of LSL. The IOP reduction achieved by LSL was 7.0±5.1 mm Hg. In a subgroup of 54 eyes with 3 scleral flap sutures, there was no significant difference in IOP reduction in a comparison of corner and central sutures (<italic>P</italic>=0.4). The reduction of IOP after LSL was not significantly correlated with the number of respectively remaining scleral flap sutures (<italic>P</italic>=0.17). There was no correlation between the time of LSL and IOP reduction (<italic>P</italic>=0.96).</p> </sec> <sec> <title>Conclusion:</title> <p>The reduction of IOP after LSL is not related to suture selection or the number of remaining scleral flap sutures.</p> </sec> </abstract>