3-T Breast Diffusion-Weighted MRI by Echo-Planar Imaging With Spectral Spatial Excitation or With Additional Spectral Inversion Recovery. Issue 3 (May 2015)

• Record Type: Journal Article
• Authors: Jacobsen, Megan C.; Dogan, Basak E.; Adrada, Beatriz E.; Plaxco, Jeri Sue; Wei, Wei; Son, Jong Bum; Hazle, John D.; Ma, Jingfei
• Is Part Of: Journal of computer assisted tomography. Volume 39:Issue 3(2015)
• Publication Date: 2015-05
• Subjects: Tomography -- Periodicals; Tomography -- Periodicals; Tomography; Periodicals; 616.0757
• DOI: 10.1097/RCT.0000000000000223
• Languages: English
• ISSNs: 0363-8715

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Objective</title> <p>To compare conventional diffusion-weighted imaging (DWI) with spectral spatial excitation (cDWI) and an enhanced DWI with additional adiabatic spectral inversion recovery (eDWI) for 3-T breast magnetic resonance imaging (MRI).</p> </sec> <sec> <title>Methods</title> <p>Twenty-four patients were enrolled in the study with both cDWI and eDWI. Three breast radiologists scored cDWI and eDWI images of each patient for fat-suppression quality, geometric distortion, visibility of normal structure and biopsy-proven lesions, and overall image quality. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and apparent diffusion coefficient (ADC) for evaluable tissues were measured. Statistical tests were performed for qualitative and quantitative comparisons.</p> </sec> <sec> <title>Results</title> <p>Diffusion-weighted imaging with spectral spatial excitation yielded significantly higher CNR and SNR on a lesion basis, and higher glandular CNR and SNR and muscle SNR on a patient basis. Enhanced DWI also yielded significantly higher qualitative scores in all categories. No significant difference was found in ADC values.</p> </sec> <sec> <title>Conclusions</title> <p>Enhanced DWI provided superior image quality and higher CNR and SNR on a lesion basis. Enhanced DWI can replace cDWI for 3-T breast DWI.</p> </sec> </abstract>