Interferon-Alpha Caused Reversible Parkinsonism. Issue 3 (May 2015)

• Record Type: Journal Article
• Authors: Lu, Chieh-Sheng; Kao, Wei-Yau; Lin, Jiann-Chyun; Chang, Ping-Ying
• Is Part Of: Clinical neuropharmacology. Volume 38:Issue 3(2015)
• Publication Date: 2015-05
• Subjects: Neuropharmacology -- Periodicals; 615.78
• DOI: 10.1097/WNF.0000000000000087
• Languages: English
• ISSNs: 0362-5664

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Abstract</title> <p>Interferon has been used to treat chronic viral hepatitis and several malignancies. However, it may cause various neuropsychiatric adverse effects including parkinsonism. We report a rare case of interferon alpha-2a therapy–related parkinsonism in a 67-year-old man with metastatic papillary renal cell carcinoma and our experience of using Tc-99m-TRODAT-1 single photon emission computed tomography (SPECT) as a tool for evaluation of parkinsonism. Physicians should be alert to the possibility of interferon alpha-2a–related parkinsonism.</p> </sec> </abstract>