Microfluidic Single‐Cell Analysis with Affinity Beads. Issue 22 (29th January 2015)

• Record Type: Journal Article
• Authors: Werner, Michael; Palankar, Raghavendra; Arm, Loïc; Hovius, Ruud; Vogel, Horst
• Is Part Of: Small. Volume 11:Issue 22(2015)
• Page Start: 2607
• Page End: 2613
• Publication Date: 2015-01-29
• Subjects: Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201402650
• Languages: English
• ISSNs: 1613-6810

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="smll201402650-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>A micrometer‐sized affinity bead</bold> (red) is (i) taken up into a cell by phagocytosis, (ii) photochemically released from phagosomes, (iii) optically trapped by the cell, and (iv) isolated by cell lysis for subsequent analysis of captured intracellular analyte (green). <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgjrk4wktk" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>