Cell compatibility of a maghemite/polymer biomedical nanoplatform. Issue 5 (August 2015)

• Record Type: Journal Article
• Authors: Ali, Lamiaa M.A.; Piñol, Rafael; Villa-Bellosta, Ricardo; Gabilondo, Lierni; Millán, Angel; Palacio, Fernando; Sorribas, Victor
• Is Part Of: Toxicology in vitro. Volume 29:Issue 5(2015)
• Page Start: 962
• Page End: 975
• Publication Date: 2015-08
• Subjects: Toxicity testing -- In vitro -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.1016/j.tiv.2015.04.003
• Languages: English
• ISSNs: 0887-2333

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st130">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0235">Toxicity is mostly determined by the amount of polymer uptake, independently of size effects.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0240">Internalization occurs through clathrin-dependent endocytosis.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0245">IONP are directed and accumulated in lysosomes.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0250">Cell death occurs by necrosis.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0255">Large IONP seem the most adequate for intracellular magnetic applications.</p> </list-item> </list> </p> </sec> </abstract>