Genetic variability at promoters of IL-18 (pro-) and IL-10 (anti-) inflammatory gene affects susceptibility and their circulating serum levels: An explorative study of prostate cancer patients in North Indian populations. Issue 1 (July 2015)

• Record Type: Journal Article
• Authors: Dwivedi, Shailendra; Goel, Apul; Khattri, Sanjay; Mandhani, Anil; Sharma, Praveen; Misra, Sanjeev; Pant, Kamlesh Kumar
• Is Part Of: Cytokine. Volume 74:Issue 1(2015)
• Page Start: 117
• Page End: 122
• Publication Date: 2015-07
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.04.001
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st095">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0140">IL-18 and IL-10 promoter genetic variants affect prostate carcinoma susceptibility.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0145">IL-18 and IL-10 promoter genetic variants affect circulatory protein levels.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0150">IL-18 protein levels showed a trend of GG &gt; GC &gt; CC at −137 of IL-18 in PCa.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0155">IL-10 protein levels showed a trend of CC &gt; CT &gt; TT at −819 of IL-10 in all groups.</p> </list-item> </list> </p> </sec> </abstract>