Association of combinations of interleukin-10 and pro-inflammatory cytokine gene polymorphisms with dengue hemorrhagic fever. Issue 1 (July 2015)

• Record Type: Journal Article
• Authors: Alagarasu, K.; Bachal, R.V.; Tillu, H.; Mulay, A.P.; Kakade, M.B.; Shah, P.S.; Cecilia, D.
• Is Part Of: Cytokine. Volume 74:Issue 1(2015)
• Page Start: 130
• Page End: 136
• Publication Date: 2015-07
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.03.021
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st050">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0125">SNPs in <italic>TNF</italic>, <italic>IFNG</italic>, <italic>IL1B</italic>, <italic>IL8</italic>, <italic>IL0</italic>, <italic>IL17A</italic> and <italic>IL17F</italic> genes were investigated in 132 dengue cases and 108 healthy controls.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0130"> <italic>IL8</italic> rs4973 A/T and <italic>IL10</italic> rs1800871 A/G genotypes were negatively associated with dengue hemorrhagic fever (DHF).</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0135">Combinations of <italic>IL10</italic> rs1800871 and pro-inflammatory cytokine genotypes influence the risk of DHF.</p> </list-item> </list> </p> </sec> </abstract>