Quantification of tumor infiltrating Foxp3+ regulatory T cells enables the identification of high-risk patients for developing synchronous cancers over upper aerodigestive tract. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Wang, Wen-Lun; Chang, Wei-Lun; Yang, Hsiao-Bai; Chang, I-Wei; Lee, Ching-Tai; Chang, Chi-Yang; Lin, Jaw-Town; Sheu, Bor-Shyang
• Is Part Of: Oral oncology. Volume 51:Issue 7(2015:Jul.)
• Page Start: 698
• Page End: 703
• Publication Date: 2015-07
• Subjects: Mouth -- Cancer -- Periodicals; Mouth -- Tumors -- Periodicals; Mouth Diseases -- Periodicals; Mouth Neoplasms -- Periodicals; Bouche -- Cancer -- Périodiques; Bouche -- Tumeurs -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9943105
• DOI: 10.1016/j.oraloncology.2015.04.015
• Languages: English
• ISSNs: 1368-8375

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">Synchronous cancers over upper aerodigestive tract lead to poor prognosis.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">The tumor infiltrating Foxp3+ regulatory T cells were higher in synchronous SCC.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">The Foxp3+ regulatory T cell density in tumor was correlated with serum IL-10 level.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">The serum IL-10 level was higher in synchronous SCC than in non-synchronous ones.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0025">Foxp3+ Treg number stratifies the synchronous cancer risk for surveillance program.</p> </list-item> </list> </p> </sec> </abstract>