Cancer stem cells and field cancerization of Oral squamous cell carcinoma. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Simple, M.; Suresh, Amritha; Das, Debashish; Kuriakose, Moni A.
• Is Part Of: Oral oncology. Volume 51:Issue 7(2015:Jul.)
• Page Start: 643
• Page End: 651
• Publication Date: 2015-07
• Subjects: Mouth -- Cancer -- Periodicals; Mouth -- Tumors -- Periodicals; Mouth Diseases -- Periodicals; Mouth Neoplasms -- Periodicals; Bouche -- Cancer -- Périodiques; Bouche -- Tumeurs -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9943105
• DOI: 10.1016/j.oraloncology.2015.04.006
• Languages: English
• ISSNs: 1368-8375

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st115">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0030"> <label></label> <p id="p0220">Field cancerization refers to transformed cells in the tumor-adjacent fields.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0195">Stem cells in this field, are possible candidates for amassing transforming mutations.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0200">Tumorigenic/migratory cancer stem cells can effect mono-/polyclonal FC models.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0205">Molecular evidence for association of FC with CSC-specific markers.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0210">CSCs proposed to be tools of FC; CSC markers may be predictive of disease relapse in OSCC.</p> </list-item> </list> </p> </sec> </abstract>