Endocannabinoid signaling at the periphery: 50 years after THC. (May 2015)

• Record Type: Journal Article
• Authors: Maccarrone, Mauro; Bab, Itai; Bíró, Tamás; Cabral, Guy A.; Dey, Sudhansu K.; Di Marzo, Vincenzo; Konje, Justin C.; Kunos, George; Mechoulam, Raphael; Pacher, Pal; Sharkey, Keith A.; Zimmer, Andreas
• Is Part Of: Trends in pharmacological sciences. Volume 36:Number 5(2015)
• Page Start: 277
• Page End: 296
• Publication Date: 2015-05
• Subjects: Pharmacology -- Periodicals; Pharmacology -- trends -- Periodicals; Pharmacologie -- Périodiques; Pharmacology; Electronic journals; Periodicals; 615.1
• DOI: 10.1016/j.tips.2015.02.008
• Languages: English
• ISSNs: 0165-6147

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Fifty years ago the psychoactive ingredient of <italic>Cannabis sativa</italic>, THC, was isolated.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0010">We critically review the current status of eCB function in peripheral organs.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0015">We discuss the relevance of the peripheral ECS in human health and disease pathogenesis.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0020">We highlight emerging challenges and therapeutic hopes.</p> </list-item> </list> </p> </sec> </abstract>