Pharmaceutical Nanotechnology: Blended Nanoparticle System Based on Miscible Structurally Similar Polymers: A Safe, Simple, Targeted, and Surprisingly High Efficiency Vehicle for Cancer Therapy (Adv. Healthcare Mater. 8/2015). Issue 8 (3rd June 2015)

• Record Type: Journal Article
• Authors: Tao, Wei; Zhang, Jinxie; Zeng, Xiaowei; Liu, Danny; Liu, Gan; Zhu, Xi; Liu, Yanlan; Yu, Qingtong; Huang, Laiqiang; Mei, Lin
• Is Part Of: Advanced healthcare materials. Volume 4:Issue 8(2015)
• Page Start: 1260
• Page End: 1260
• Publication Date: 2015-06-03
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201570050
• Languages: English
• ISSNs: 2192-2640

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adhm201570050-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>On page 1203, a novel blended nanoparticle (NP) system for the delivery of anticancer drugs and its surprisingly high efficacy for cancer chemotherapy by blending a targeting polymer folic acid‐poly(ethylene glycol)‐b‐poly(lactide‐co‐glycolide) (FA‐PEG‐b‐PLGA) and a miscible structurally similar polymer D‐α‐tocopheryl polyethylene glycol 1000 succinate‐poly(lactide‐co‐glycolide) (TPGS‐PLGA) are reported by X. Zeng, L. Huang, L. Mei, and colleagues. This blended NP system can be achieved through a simple and effective nanoprecipitation technique, possessing unique properties. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgjr8z91n5" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>