Abnormal meiotic recombination with complex chromosomal rearrangement in an azoospermic man. Issue 6 (June 2015)

• Record Type: Journal Article
• Authors: Wang, Liu; Iqbal, Furhan; Li, Guangyuan; Jiang, Xiaohua; Bukhari, Ihtisham; Jiang, Hanwei; Yang, Qingling; Zhong, Liangwen; Zhang, Yuanwei; Hua, Juan; Cooke, Howard J.; Shi, Qinghua
• Is Part Of: Reproductive biomedicine online. Volume 30:Issue 6(2015)
• Page Start: 651
• Page End: 658
• Publication Date: 2015-06
• Subjects: Human reproductive technology -- Periodicals; Human embryo -- Periodicals; Reproduction -- Periodicals; 616.692
• DOI: 10.1016/j.rbmo.2015.02.015
• Languages: English
• ISSNs: 1472-6483

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">Subject was azoospermic reciprocal translocation 46, XY, t(5;7;9;13) carrier.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">H&amp;E stained testicular sections revealed no spermatids or sperm in the patient.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">TUNEL assay demonstrated apoptotic cells in testicular sections of translocation carrier.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">Increase in zygotene and decrease in the pachytene spermatocytes were observed in subject.</p> </list-item> <list-item id="u0030"> <label></label> <p id="p0030">Significant decrease in the recombination frequency of the translocation carrier</p> </list-item> </list> </p> </sec> </abstract>