Determination of a critical size calvarial defect in senile osteoporotic mice model based on in vivo micro-computed tomography and histological evaluation. Issue 1 (July 2015)

• Record Type: Journal Article
• Authors: Zhang, Yufeng; Wang, Lu; Deng, Feng; Qiu, Hongmei; Wu, Xiaohong
• Is Part Of: Archives of gerontology and geriatrics. Volume 61:Issue 1(2015:Jul./Aug.)
• Page Start: 44
• Page End: 55
• Publication Date: 2015-07
• Subjects: Aging -- Periodicals; Geriatrics -- Periodicals; Gerontology -- Periodicals; Electronic journals; 305.26
• DOI: 10.1016/j.archger.2015.01.019
• Languages: English
• ISSNs: 0167-4943

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Calvarial bone healing model was made in senile osteoporotic mice (SAMP6) firstly.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The healing ability was compared with senescence-resistant inbred strains (SAMR1).</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Less new bone within the defect were detected in SAMP6 by micro-CT study.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Less osteoblasts were observed at the defect site in SAMP6 by histomorphometry.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">SAMP6 show different healing ability of intramembranous ossification from SAMR1.</p> </list-item> </list> </p> </sec> </abstract>