Predictive role of erythrocyte macrocytosis during treatment with pemetrexed in advanced non-small cell lung cancer patients. Issue 3 (June 2015)

• Record Type: Journal Article
• Authors: Buti, Sebastiano; Bordi, Paola; Tiseo, Marcello; Bria, Emilio; Sperduti, Isabella; Di Maio, Massimo; Panni, Stefano; Novello, Silvia; Rapetti, Simonetta Grazia; Pilotto, Sara; Genestreti, Giovenzio; Rossi, Antonio; Pezzuolo, Debora; Camisa, Roberta; Tortora, Giampaolo; Ardizzoni, Andrea
• Is Part Of: Lung cancer. Volume 88:Issue 3(2015:Jun.)
• Page Start: 319
• Page End: 324
• Publication Date: 2015-06
• Subjects: Lungs -- Cancer -- Periodicals; Lung Neoplasms -- Abstracts; Lung Neoplasms -- Periodicals; Poumons -- Cancer -- Périodiques; Lungs -- Cancer; Periodicals; Electronic journals; Electronic journals; 616.99424
• DOI: 10.1016/j.lungcan.2015.03.016
• Languages: English
• ISSNs: 0169-5002

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Pemetrexed based chemotherapy is a standard for advanced non-small cell lung cancer.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Clinical and laboratory data were retrospectively obtained from 191 patients.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">All patients were treated with pemetrexed based chemotherapy.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Pemetrexed increased mean corpuscular volume (MCV).</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">The MCV increment correlated with better DCR, PFS and OS.</p> </list-item> </list> </p> </sec> </abstract>