2-A-D-19. Functional navigated tDCS for patients with non-fluent aphasia. Issue 6 (June 2015)

• Record Type: Journal Article
• Authors: Fujiwara, Toshiyuki; Kawakami, Michiyuki; Masakado, Yoshihisa; Liu, Meigen
• Is Part Of: Clinical neurophysiology. Volume 126:Issue 6(2015:Jun.)
• Page Start: e59
• Page End: e60
• Publication Date: 2015-06
• Subjects: Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electromyography -- Periodicals; Neurology -- Periodicals; 612.8
• DOI: 10.1016/j.clinph.2015.02.041
• Languages: English
• ISSNs: 1388-2457

Abstract

<abstract xml:lang="en" abstract-type="author" id="ab005"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <p id="sp005">Inferior frontal gyrus (IFG) plays an important role for recovery of non-fluent aphasia. It is not, however, clear which side of IFG activation is better for functional recovery of non-fluent aphasia. We applied tDCS over IFG with using MRI guided navigation system and assessed reaction time for naming task. We applied both anodal and cathodal tDCS over left IFG. Electrodes were placed over both IFG. Anode electrode was placed over left IFG and cathode electrode was over right IFG in anodal tDCS. In cathodal tDCS, anode electrode was placed over right IFG and cathode electrode was over left IFG. Stimulus intensity was set at 2 mA and tDCS was applied for 10 min. Before and after tDCS, we assessed reaction time for naming task with Boston naming test. Anodal tDCS reduced reaction time in one patient (case A) and cathodal tDCS did in the other one patient (case B). We applied 7 days tDCS combined with speech therapy. Anodal tDCS in case A and cathodal tDCS in case B combined with speech therapy improved reaction time and correct answer rate. It is supposed that individually-tailored treatment is necessary to apply tDCS for patients with aphasia.</p> </sec> </abstract>