1-A-D-3. An ultrasonography with nerve conduction study on the diaphragm in neuromuscular disorders. Issue 6 (June 2015)

• Record Type: Journal Article
• Authors: Noda, Yoshikatsu; Sekiguchi, Kenji; Kohara, Nobuo; Kowa, Hisatomo; Kanda, Fumio; Toda, Tatsushi
• Is Part Of: Clinical neurophysiology. Volume 126:Issue 6(2015:Jun.)
• Page Start: e57
• Publication Date: 2015-06
• Subjects: Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electromyography -- Periodicals; Neurology -- Periodicals; 612.8
• DOI: 10.1016/j.clinph.2015.02.030
• Languages: English
• ISSNs: 1388-2457

Abstract

<abstract xml:lang="en" abstract-type="author" id="ab005"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title id="st005">Objective</title> <p id="sp005">An ultrasonography (USG) with nerve conduction study, in addition to a standard pulmonary function test, was performed to evaluate diaphragm function in various neuromuscular disorders.</p> </sec> <sec> <title id="st010">Methods</title> <p id="sp010">We evaluated 25 neuromuscular patients: 12 amyotrophic lateral sclerosis, 3 myasthenia gravis, 3 myopathy, 3 neuropathy, and 3 central nervous system disorders. USG of the diaphragm was performed in a supine position using a linear probe over the intercostal space at the anterior axillary line. Diaphragm muscle thickness was measured at the end-expiratory period. The amplitude of compound muscle action potentials (CMAP) was obtained by phrenic nerve stimulation with a surface electrode. The recording electrode was placed 5 cm above the xiphoid process, and the reference electrode was placed over the ipsilateral costal margin.</p> </sec> <sec> <title id="st015">Results</title> <p id="sp015">There was a significant correlation between diaphragm thickness and forced vital capacity (FVC) (<italic>r</italic> = .78) and also between CMAP amplitudes and FVC (<italic>r</italic> = .74).</p> </sec> <sec> <title id="st020">Conclusions</title> <p id="sp020">USG of the diaphragm is a novel method for objective evaluation of pulmonary function in neuromuscular disorders without undue patient effort. In addition, USG is easy-to-use at the patient's bedside and non-invasive, and has the advantage of presuming respiratory function without cooperation of the patients.</p> </sec> </abstract>