Alveolar macrophages and type I IFN in airway homeostasis and immunity. Issue 5 (May 2015)

• Record Type: Journal Article
• Authors: Divangahi, Maziar; King, Irah L.; Pernet, Erwan
• Is Part Of: Trends in immunology. Volume 36:Issue 5(2015)
• Page Start: 307
• Page End: 314
• Publication Date: 2015-05
• Subjects: Immunology -- Periodicals; 571.96
• DOI: 10.1016/j.it.2015.03.005
• Languages: English
• ISSNs: 1471-4906

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">The airways are constantly patrolled by alveolar macrophages.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Alveolar macrophages are indispensable for tissue homeostasis and host defense.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Alveolar macrophages are the major source of type I IFN following immune challenge.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Type I IFNs regulate antimicrobial and inflammatory responses of pulmonary macrophages.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Eicosanoids modulate type I IFN signaling and production following pathogen invasion.</p> </list-item> </list> </p> </sec> </abstract>