Epigenetic and transcriptional control of Foxp3+ regulatory T cells. Issue 1 (February 2015)

• Record Type: Journal Article
• Authors: Huehn, Jochen; Beyer, Marc
• Is Part Of: Seminars in immunology. Volume 27:Issue 1(2015)
• Page Start: 10
• Page End: 18
• Publication Date: 2015-02
• Subjects: Immunology -- Periodicals; Allergy and Immunology -- Periodicals; Immunity -- Periodicals; Immunologie -- Périodiques; Electronic journals; 616.079
• DOI: 10.1016/j.smim.2015.02.002
• Languages: English
• ISSNs: 1044-5323

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">T_reg cells are essential for initiation and maintenance of immunological tolerance.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Foxp3 is the lineage-specifying transcription factor.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Foxp3 expression is controlled on transcriptional and epigenetic level.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Foxp3 itself governs the gene expression program of T_reg cells.</p> </list-item> </list> </p> </sec> </abstract>