Adhesion of monocytes to periodontal fibroblasts requires activation of NOD1/2- and TLR4-mediated LFA-1 and VLA-4. Issue 6 (June 2015)

• Record Type: Journal Article
• Authors: Liu, Jianru; Liu, Wenyi; Xie, Ying; Wang, Yixiang; Ouyang, Xiangying
• Is Part Of: Archives of oral biology. Volume 60:Issue 6(2015:Jun.)
• Page Start: 834
• Page End: 844
• Publication Date: 2015-06
• Subjects: Mouth -- Periodicals; Mouth -- Diseases -- Periodicals; Dentistry -- Periodicals; Electronic journals; 617.6005
• DOI: 10.1016/j.archoralbio.2014.12.012
• Languages: English
• ISSNs: 0003-9969

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">NOD1/2 and TLR 4 were highly expressed in the gingiva of patients with periodontitis.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">NOD1/2 and TLR4 regulated the activity of LFA-1 and VLA-1 in cells of U937.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">NOD1/2 and TLR4 mediated the binding of U937 cells to periodontal fibroblasts.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">LFA-1 and VLA-4 are responsible for monocyte-periodontal fibroblasts adhesion.</p> </list-item> </list> </p> </sec> </abstract>