Thioimidazoline based compounds reverse glucocorticoid resistance in human acute lymphoblastic leukemia xenografts1. Issue 22 (14th June 2015)

• Record Type: Journal Article
• Authors: Toscan, Cara E.; Rahimi, Marwa; Bhadbhade, Mohan; Pickford, Russell; McAlpine, Shelli R.; Lock, Richard B.
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 22(2015)
• Page Start: 6299
• Page End: 6312
• Publication Date: 2015-06-14
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00779h
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjqwj29sg" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Glucocorticoids form a critical component of chemotherapy regimens for pediatric acute lymphoblastic leukemia and initial poor response to glucocorticoid therapy is predictive of inferior outcome.</p> </abstract>