Do Asian women do as well as their Caucasian counterparts in IVF treatment: Cohort study. Issue 6 (16th December 2014)

• Record Type: Journal Article
• Authors: Kan, Andrew; Leung, Peter; Luo, Kehui; Fay, Louise; Tan, Chunyan (Leeann)
• Is Part Of: Journal of obstetrics and gynaecology research. Volume 41:Issue 6(2015:Jun.)
• Page Start: 946
• Page End: 951
• Publication Date: 2014-12-16
• Subjects: Gynecology -- Periodicals; Obstetrics -- Periodicals; 618.1005
• DOI: 10.1111/jog.12643
• Languages: English
• ISSNs: 1341-8076

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="jog12643-sec-0001" sec-type="section"> <title>Aim</title> <p>To evaluate if there is a difference in pregnancy rate between Asian and Caucasian women when they undergo <italic>in vitro</italic> fertilization (IVF).</p> </sec> <sec id="jog12643-sec-0002" sec-type="section"> <title>Methods</title> <p>This was a retrospective cohort study set in a private reproductive medicine clinic. The study consisted of a total of 2594 patients (Asian, <italic>n</italic> = 522; Caucasian, <italic>n</italic> = 2072) undergoing IVF managed by a single doctor over a 10 year period. The main outcome measures were clinical pregnancy rate and live birth rate. Logistic regression was used to control for confounding factors.</p> </sec> <sec id="jog12643-sec-0003" sec-type="section"> <title>Results</title> <p>Asian women achieved a significantly lower clinical pregnancy and live birth rate than their Caucasian counterparts, despite replacement of more embryos. This difference was not significant after controlling for age and duration of infertility. Despite higher doses of gonadotrophin, they achieved fewer oocytes and had resultant fewer embryos for transfer or cryopreservation.</p> </sec> <sec id="jog12643-sec-0004" sec-type="section"> <title>Conclusions</title> <p>In a study designed to reduce the effect of confounding factors by looking at a large number of patients from a single IVF unit under the care of a single doctor, there does not appear to be a difference in IVF pregnancy rate as a result of race. Asian women tend to present for IVF treatment at a later age after having tried for a longer period of time and this contributes significantly to their lower pregnancy rate.</p> </sec> </abstract>