MCI of different etiologies differ on the Cognitive Assessment Battery. (11th December 2014)

• Record Type: Journal Article
• Authors: Nyström, O.; Wallin, A.; Nordlund, A.
• Is Part Of: Acta neurologica Scandinavica. Volume 132:Number 1(2015:Jul.)
• Page Start: 31
• Page End: 36
• Publication Date: 2014-12-11
• Subjects: Neurology -- Periodicals; 616.8
• DOI: 10.1111/ane.12353
• Languages: English
• ISSNs: 0001-6314

Abstract

<abstract abstract-type="main" id="ane12353-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ane12353-sec-0001" sec-type="section"> <title>Objectives</title> <p>The study aims to investigate whether patients with mild cognitive impairment (MCI) who have significant vascular disease (MCI‐vas) differ from those with no significant vascular disease (MCI‐nov) in terms of cognitive profile when assessed with the cognitive assessment battery (CAB).</p> </sec> <sec id="ane12353-sec-0002" sec-type="section"> <title>Materials and methods</title> <p>Seventy patients clinically diagnosed with MCI were included in the study, 32 were classified as MCI‐vas, and 38 as MCI‐nov, together with 40 healthy controls. CAB consists of six short tests measuring speed and attention, memory, visuospatial functions, language, and executive functions.</p> </sec> <sec id="ane12353-sec-0003" sec-type="section"> <title>Results</title> <p>The healthy controls performed better than both MCI groups on CAB. MCI‐vas patients were significantly older and had fewer years of education than MCI‐nov patients. When adjusted for age and education, MCI‐vas performed significantly worse than MCI‐nov on memory, language, and executive tests.</p> </sec> <sec id="ane12353-sec-0004" sec-type="section"> <title>Conclusions</title> <p>The results suggest that CAB can differentiate between MCI patients with and without vascular disease and that their cognitive profiles differ. Furthermore, CAB classified the patients as vascular and non‐vascular MCI with good sensitivity and specificity.</p> </sec> </abstract>