UV irradiation-induced production of monoglycosylated biglycan through downregulation of xylosyltransferase 1 in cultured human dermal fibroblasts. Issue 1 (July 2015)

• Record Type: Journal Article
• Authors: Jin, Cheng Long; Oh, Jang-Hee; Han, Mira; Shin, Min Kyeong; Yao, Cheng; Park, Chi-Hyun; Jin, Zhe Hu; Chung, Jin Ho
• Is Part Of: Journal of dermatological science. Volume 79:Issue 1(2015:Jul.)
• Page Start: 20
• Page End: 29
• Publication Date: 2015-07
• Subjects: Dermatology -- Periodicals; Skin Diseases -- Periodicals; Dermatologie -- Périodiques; 616.5005
• DOI: 10.1016/j.jdermsci.2015.03.018
• Languages: English
• ISSNs: 0923-1811

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">UV increases monoglycosylated biglycan production in cultured fibroblasts.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">UV decreases XYLT1 mRNA expression much more than XYLT2.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Only XYLT1 donwregulation induces monoglycosylated biglycan production.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">XYTL2 seems to react with only serine 42 but not with serine 47 on the biglycan core protein.</p> </list-item> </list> </p> </sec> </abstract>